Can you please provide advice on big data handling strategy?

While you will not see those that use Prolog with bioinformatics here much they are about.

  1. Reactome Pengine (GitHub) (paper)
  2. SWI-Prolog pack bio_analytics.

If you looked at my examples in the QLF post you will see that it was using author references, e.g.

uniProt_reference_authors(reference_id(entry_name(swiss_prot,“001R”,“FRG3G”),1),“Tan W.G.”).
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